Venom of Naja Sputatrix

Venom of Naja Sputatrix

 

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The chemical preparation of all our products are synthesized. These substances possesses sterile effect, so you must be fully aware of what you are purchasing hence there’s no prejudice involved in the offer and acceptance.

Available for sale here is Venom of Naja Sputatrix:

The Javan spitting cobra (Naja sputatrix), also called Indonesian cobra or Komodo spitting cobra, is a species of cobra in the family Elapidae, found in the Lesser Sunda Islands of Indonesia, including Java, Bali, Lombok, Sumbawa, Flores, Komodo, and others.

The Java spitting cobra is a medium to large sized snake and has long cervical ribs, capable of expanding to form a hood when threatened.

The body of this species is compressed dorsoventrally and posteriorly cylindrical. The average length of an adult is 1.3 metres (4.3 ft), but they can grow to a maximum of around 1.85 metres (6.1 ft).

The head is elliptical, slightly different from the neck with a short rounded snout and large nostrils.

The LD50 or (median lethal dose) of the crude venom of this species is 0.90 mg/kg IV (0.59-1.36 mg/kg).

The most significant constituents of the venom include high-molecular-weight proteins and enzymes, phospholipase A2 enzymes, postsynaptic neurotoxins and polypeptide cardiotoxins, meaning although the venom may be potent, it may not be particularly rapid-acting.

Like all cobra species, this species’ venom also consists of postsynaptic neurotoxins. However, the main components of its venom are cardiotoxins with cytotoxic activity.

In fact, polypeptide cardiotoxins make up 60% of the venom (dry weight), while postsynaptic neurotoxins make up only 4.5%. The two main neurotoxins, sputa-neurotoxin 1 (SN1) and sputa-neurotoxin 2 (SN2) isolated from the venom, are “short” neurotoxins, with 62 and 61 amino acid residues, respectively.

The IV LD50 of the two toxins are 0.09 mg/g and 0.07 mg/g, respectively, and they possess amino acid sequences similar to those of other cobra venom neurotoxins.

The venom was also found to exhibit an in vitro anticoagulant activity much stronger than most common cobra (genus Naja) venoms.

The anticoagulants, phospholipase A2 enzymes, with a molecular weight of approximately 14 kDa, make up 15% of the venom (dry weight). Very few human fatalities are attributed to this species.

Product ID: L1326
Name: Naja sputatrix
Common Name(s): Indonesian Cobra
Origin: Indonesia
Purity: >99%
Form: Lyophilized powder
Packaging: In vacuum sealed glass vials, in secured parcel.

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