Venom of Sistrurus Miliarius Barbouri

Venom of Sistrurus Miliarius Barbouri

 

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Available for sale here is Venom of Sistrurus Miliarius Barbouri:

Sistrurus miliarius barbouri is a venomous pit viper subspecies endemic to the southeastern United States.

Common names for S. m. barbouri include Barbour’s pygmy rattlesnake, dusky pygmy rattlesnake, Florida ground rattlesnake, ground rattlesnake, hog-nosed rattler, pygmy ground rattlesnake, pygmy rattler, pygmy rattlesnake, small rattlesnake, and southeastern ground rattlesnake.

Adults of S. m. barbouri grow to between 35.5 and 76.0 cm (14.0 and 29.9 in) in total length, which includes the tail (Klauber, 1943). In a study that involved 103 males and 80 females, the average total length was 53.5 cm (21.1 in).

Snellings and Collins (1997) reported a specimen measuring 80.3 cm (31.6 in) in total length, but it had been in captivity for over 12 years. The largest reported by Gloyd (1940) was one measuring 63.8 cm (25.1 in) in total length from St. Petersburg, Florida.

Wright and Wright (1957) include excerpts from Allen (1938) that describe how an assistant was bitten by S. m. barbouri in the Everglades and suffered severe pain and swelling for about 24 hours despite treatment.

Allen also quotes some statistics: according to the Florida Reptile Institute, 28 people were bitten by this subspecies in Florida between 1935 and 1937 with no deaths. Though these bites are painful, they are not considered life-threatening to people or pets.

Brown (1973) gives an average venom yield of 18 mg (dried venom) (Klauber, 1956) and LD50 values of 2.8,12.6 mg/kg IV, 6.0,6.8 mg/kg IP and 24.2 mg/kg SC for toxicity.

The venom contain disintegrins, notably barbourin which has a KGD (Lys-Gly-Asp) amino acid motif rather than the more common RGD (Arg-Gly-Asp) motif. This single amino acid alteration gives barbourin higher binding affinity for the fibrinogen receptor glycoprotein IIb/IIIa.

This receptor plays an important role in the aggregation of platelets, which then leads to the formation of a blood clot – competitive inhibition of this receptor by barbourin will decrease platelet aggregation, and thus reduce clotting.

Product ID: L1224
Name: Sistrurus miliarius barbouri
Common Name(s): Dusky Pigmy Rattlesnake
Origin: USA
Purity: >99%
Form: Lyophilized powder
Packaging: In vacuum sealed glass vials, in secured parcel.

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